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Senior Scientist, Enzymology and Assay Development

Kimia Therapeutics

Kimia Therapeutics

Berkeley, CA, USA
Posted on Saturday, May 4, 2024
Are you excited about getting in on the ground floor of a startup company poised to revolutionize small molecule drug discovery? At Kimia Therapeutics we are building a next generation drug discovery engine by combining high-throughput chemistry and screening with state-of-the-art computational approaches to accelerate the discovery of novel drugs. At Kimia, we look for collaborative teammates who are motivated by our mission and would like to play an impactful role in the growth and success of an emerging pharmaceutical company.
Job Summary
We are seeking a highly motivated and experienced Senior Scientist to join our Biology team. The successful candidate will be responsible for developing biochemical and cellular assays, as well as conducting detailed mechanistic and enzymology studies to characterize compound MOA and validation. You will work closely with the protein production and high throughput screening teams to bring new targets online and advance candidate drugs from hit to lead. This role offers exceptional hands-on learning opportunities and involves close collaboration with our scientists on innovative early-stage drug discovery programs.

Responsibilities

  • Design, develop, and validate biochemical assays to support new target initiation, hit identification and MOA studies.
  • Optimize assay performance for sensitivity, specificity, and high-throughput compatibility.
  • Contribute to target selection/validation and in vitro MOA studies for small molecule drug candidates.
  • Analyze and interpret screening data, identify promising hits, and contribute to the selection of development candidates.
  • Collaborate with cross-functional teams to integrate assays into discovery pipelines.
  • Document and maintain accurate records of assay protocols and experimental data.
  • Interpret, summarize, and present research findings to multidisciplinary project teams.

Qualifications

  • Ph.D. in biochemistry, cell biology, or a related field with 2+ years industry experience, preferably in small molecule drug discovery.
  • Strong hands-on experience in designing and validating biochemical and cellular functional assays.
  • Expert knowledge of enzymology and hand-on experience with MOA studies for small molecule compounds.
  • Experience with high-throughput assay development is a plus.
  • Strong understanding of the drug discovery process and demonstrated experience working in cross-functional teams.
  • Proven ability to interpret, summarize, and present research findings to multidisciplinary project teams.
  • Strong communication and interpersonal skills
  • Passion for drug discovery and a desire to contribute to the development of novel therapeutics.
We offer a vibrant startup environment where every member of the Kimia team plays an important role in shaping our science and our culture. Kimia offers competitive pay, participation in our stock option plan, and comprehensive benefits. At Kimia we believe that a diverse, open and inclusive environment is key to our success. We are proud to be equal opportunity employer and will consider all applicants for employment.
Full vaccination against COVID-19 is a condition of employment at Kimia. If you are unable to receive a COVID-19 vaccine due to a disability, or serious medical condition, or because it would violate your sincerely held religious belief, you will have an opportunity to request a reasonable accommodation.
Note to external recruiters: Please do not submit any agency resumes. Kimia will not be responsible for any fees related to resumes that are unsolicited.